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reductive acetyl coenzyme A pathway

State Icon Reaction EC-Number Confidence maximal confidence score from EnzymeDetector
CO + H2O + oxidized_ferredoxin <=> CO2 + reduced_ferredoxin_[iron-sulfur]_cluster + H+ 1.2.7.4 anaerobic carbon monoxide dehydrogenase

formate + acceptor <=> CO2 + reduced_acceptor 1.17.99.7 formate dehydrogenase (acceptor)

a_[methyl-Co(III)_corrinoid_Fe-S_protein] + tetrahydrofolate <=> [Co(I)_corrinoid_Fe-S_protein] + 5-methyltetrahydrofolate 2.1.1.258 5-methyltetrahydrofolate---corrinoid/iron-sulfur protein Co-methyltransferase

formate + NADP+ <=> CO2 + NADPH 1.17.1.10 formate dehydrogenase (NADP+)
1.17.1.9 formate dehydrogenase


acetyl-CoA + [Co(I)_corrinoid_Fe-S_protein] + H+ <=> CO + a_[methyl-Co(III)_corrinoid_Fe-S_protein] + CoA 2.3.1.169 CO-methylating acetyl-CoA synthase

5,10-methylenetetrahydrofolate + NADP+ <=> 5,10-methenyltetrahydrofolate + NADPH 1.5.1.15 methylenetetrahydrofolate dehydrogenase (NAD+)
1.5.1.5 methylenetetrahydrofolate dehydrogenase (NADP+)


tetrahydrofolate + ATP + formate <=> 10-formyltetrahydrofolate + ADP + phosphate 6.3.4.3 formate---tetrahydrofolate ligase

5-methyltetrahydrofolate + oxidized_ferredoxin <=> 5,10-methylenetetrahydrofolate + reduced_ferredoxin_[iron-sulfur]_cluster + H+ 1.5.1.20 methylenetetrahydrofolate reductase [NAD(P)H]
1.5.7.1 methylenetetrahydrofolate reductase (ferredoxin)


5,10-methenyltetrahydrofolate + H2O <=> 10-formyltetrahydrofolate + H+ 3.5.4.9 methenyltetrahydrofolate cyclohydrolase

formate + NAD+ <=> CO2 + NADH 1.17.1.10 formate dehydrogenase (NADP+)
1.17.1.9 formate dehydrogenase


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